Publications

Reflecting and Looking Forward – The Role of Veterinary Scientific Journals in Veterinary Research and Medicine
Slovenian Veterinary Research

A 2023 Nobel Prize in Physiology or Medicine: Pathway for Next Generation of Vaccines
Slovenian Veterinary Research

PWS-Associated Genes, Their Imprinting, and Expression Pattern
Prader–Willi syndrome (PWS, OMIM #176270) and Schaaf–Yang syndrome (SYS, OMIM #615547) are rare autosomal-dominant, imprinted genetic disorders caused by the loss of one or more normally active paternal genes in the chromosomal region of 15q11-q13, called the PWS region.

Scholarly Community Encyclopedia
adapted from: 10.3390/ijms241713109

Cell-specific secretory granule sorting mechanisms: the role of MAGEL2 and retromer in hypothalamic regulated secretion
Keywords: secretory granule, MAGEL2, anterograde and retrograde protein sorting, retromer, neuroendocrine cells, WASH complex, Prader-Willi and Schaaf-Yang syndromes, hormones and neuropeptides

Front. Cell Dev. Biol. 11:1243038

Hormonal Imbalances in Prader–Willi and Schaaf–Yang Syndromes Imply the Evolution of Specific Regulation of Hypothalamic Neuroendocrine Function in Mammals
Keywords: PWS; SYS; imprinting; hormone secretion; secretory granule; hypothalamus; neuroendocrine function; retromer; MAGEL2; NDN; SNORD116; MKRN3

Int. J. Mol. Sci. 2023, 24(17), 13109

Oxysterols and bile acid act as signaling molecules that regulate cholesterol homeostasis: Nuclear receptors LXR, FXR, and Fibroblast Growth Factor 15/19
Publication date: 2020
Book: Mammalian Sterols
Pages: 117-143
Publisher: Springer, Cham

A cancer-specific ubiquitin ligase drives mRNA alternative polyadenylation by ubiquitinating the mRNA 3′ end processing complex
Keywords: 3′ UTR shortening; 3′ end processing complex; CFIm25; HUWE1; MAGE-A11; PCF11; PTEN; alternative polyadenylation; cyclin D2; ubiquitin

Mol Cell. 2020 Mar 19;77(6):1206-1221.e7

Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase
Keywords: Axin; PAGE4; PARylation; RNF146; TNKS; Tankyrase; Wnt; cancer-testis antigen; prostate; β-catenin

Cell Rep. 2020 Jul 21;32(3):107922

Translational repression of G3BP in cancer and germ cells suppresses stress granules and enhances stress tolerance
Keywords: DDX5; G3BP; MAGE-B2; RNA binding protein; cancer; cancer-testis antigen; spermatogonial stem cells; stress granule; testis; translation

Mol Cell. 2020 Aug 20;79(4):645-659.e9

A Novel Locus Predicts Spermatogenic Recovery among Childhood Cancer Survivors Exposed to Alkylating Agents
Cancer Res. 2020 Sep 1;80(17):3755-3764

Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production
Keywords: Cell Biology; Neurodevelopment; Neuroscience; Protein traffic; iPS cells

JCI Insight. 2020 Sep 3;5(17):e138576

Emerging roles of the MAGE protein family in stress response pathways
Keywords: AMP-activated kinase (AMPK); DNA damage response; E3 ligase; E3 ubiquitin ligase; Fe-S cluster; MAGE; Prader-Willi syndrome; Schaaf-Yang syndrome; alternative polyadenylation; apoptosis; cancer; cancer-testis antigen; cell metabolism; melanoma antigen; metabolism; p53; spermatogenesis; stress adaptation; stress granule; stress response; ubiquitin; ubiquitination

J Biol Chem. 2020 Nov 20;295(47):16121-16155.

MAGE cancer-testis antigens protect the mammalian germline under environmental stress
Sci Adv. 2019 May 29;5(5):eaav4832.

Cellular and disease functions of the Prader–Willi Syndrome gene MAGEL2
Keywords: MAGEL2; Prader–Willi Syndrome; actin; endosomal sorting; ubiquitin

Biochem J. 2017 Jun 16;474(13):2177-2190

MAGE gene family expression in pediatric medulloblastoma: frequency and possible therapeutic target
Cancer Res (2017) 77 (13_Supplement): 4880.

γKlotho is a novel marker and cell survival factor in a subset of triple negative breast cancers
Keywords: LCTL; gamma Klotho; FGF; breast cancer; cancer therapy; ROS; oxidative stress; oncogene

Oncotarget. 2016 Jan 19;7(3):2611-28